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Missed Periods Hormone Check

Seven results from one sample: LH, FSH, prolactin, testosterone, oestradiol, SHBG and the free androgen index.

  • Doctor-reviewed results
  • Laboratory analysis
  • 1 to 2 working days from lab receipt
  • No fasting required
Missed Periods Hormone Check, home test kit

What’s included

7 markers measured

  • LH

    Luteinising hormone, measured together with FSH. In women whose periods have stopped, high LH and FSH before age 40 suggest premature ovarian insufficiency, while normal or low levels point to causes such as weight loss, stress or excessive exercise. A normal FSH with normal or moderately raised LH may be seen in polycystic ovary syndrome.

  • FSH

    Follicle-stimulating hormone. As the ovaries become less active in the years before the menopause, less feedback reaches the pituitary gland and FSH rises. Levels can swing sharply from day to day during this change, then stay high after the menopause.

  • Prolactin

    Prolactin is a hormone often checked when periods stop. Mild rises are most often due to stress or medicines such as antipsychotics, and can also be caused by pregnancy, breastfeeding, recent exercise or a difficult blood draw. Higher or persistent rises can point to a pituitary growth or an underactive thyroid and may need specialist assessment.

  • Testosterone (total)

    The total amount of testosterone in the blood, used to check men for testosterone deficiency (hypogonadism), best taken fasting between 9 and 11am. A low or borderline result is usually repeated alongside FSH, LH, SHBG and prolactin. Free testosterone, estimated from total testosterone, SHBG and albumin, gives a more reliable picture.

  • Oestradiol

    An oestrogen hormone, often checked with FSH, LH and prolactin when periods have stopped. A low level can point to early loss of ovarian function (with a high FSH), a raised prolactin, or causes such as weight loss, stress or heavy exercise. Results are not reliable during any hormonal treatment.

  • SHBG

    Sex hormone-binding globulin, a protein that affects how much testosterone is free and active. It is used with total testosterone to work out the free androgen index, and a low SHBG can mean more free testosterone even when total testosterone looks normal. Insulin lowers SHBG, so it also hints at insulin resistance.

  • Free androgen index

    Free androgen index, a ratio calculated from testosterone and SHBG. It is most useful in women; in men, a calculated free testosterone is usually a better guide.

Overview

When periods stop or become very infrequent, no single hormone gives the answer. It is the pattern across LH, FSH, prolactin, testosterone, oestradiol and SHBG that a doctor reads, and this panel gives all six plus the free androgen index from one sample. Having it done before a GP appointment can save a round trip.

Periods that have stopped or become very infrequent have several common explanations, and they are told apart by the pattern across these hormones rather than by any single one. This is a set a doctor may ask for first. Training load, weight change, stress and thyroid problems all affect it, so the report reads the seven results together and explains which pattern they fit and what a GP or gynaecologist would usually look at next.

Who this is for and who it isn’t

Who it’s for

  • Women aged 18 and over
  • Women whose periods have stopped or become very infrequent
  • Anyone whose periods did not return after coming off contraception

Who it isn’t for

  • This does not include a pregnancy test, and pregnancy is the first thing to exclude when periods stop, so do that before ordering. It also does not include thyroid function, which is a common and easily missed explanation; the Women's Hormone & Thyroid Check includes thyroid tests, but not testosterone or SHBG. Blood hormones cannot look at the ovaries themselves, so an ultrasound scan is sometimes part of the answer, and your GP can arrange one.
  • Anyone with a new, severe or worsening symptom: contact your GP or call NHS 111. A test you buy today is not a substitute for being examined.

Common reasons people choose this test

  • Periods that have stopped for three months or more
  • Periods that have become very infrequent or unpredictable
  • Acne or unwanted hair growth alongside irregular cycles
  • Coming off hormonal contraception and periods not returning
  • Heavy training or significant weight change alongside missed periods

These are reasons people choose to test, not signs that something is wrong. A result is one part of a picture your doctor puts together with your history and an examination.

What your result looks like

Every result is shown with the unit and the reference range exactly as the laboratory reported it, with the doctor’s note underneath.

Example reportIllustrative, not a real result
  • LHIn range
    Result
    5.9 IU/L
    Range
    2.4–12.6 (day 2–5)
  • FSH▲ High
    Result
    34 IU/L
    Range
    3.5–12.5 (day 2–5)
  • ProlactinIn range
    Result
    280 mIU/L
    Range
    102–496 (women)

Doctor’s note (example)

FSH above 30 with irregular periods and symptoms points towards the menopause transition. Under 45 it is repeated in six weeks before any conclusion.

…and 4 more markers. Values above are examples. Your report shows your own results with the laboratory’s units and reference range for your age and sex, reviewed, signed and released by a GMC-registered doctor.

How it works

  1. Your kit arrivesPosted to your door, with instructions and what you need to send your sample back.
  2. You take your sampleFinger-prick sample at home, or a clinic blood draw, your choice
  3. The laboratory analyses itYour sample is processed for the measurements included in this test. Lab processing typically takes 1 to 2 working days from receipt of your sample.
  4. A doctor reviews and releases itA GMC-registered doctor reads every result and signs the report before it reaches you.
Sample
Home finger-prick kit
Preparation
Read instructions below
Who it's for
Women · ages 18+

How to prepare

Wash your hands with soap and warm water before you start. Do not take the sample from a finger, or any area of skin, where hormone cream or gel has been applied, for example HRT or testosterone gel. If you apply gel to your hands, take the sample from the other hand. Hormone on the skin can get into the sample and give a falsely high result.

What we can and can’t tell you

The reference range beside each result is the laboratory’s own. A result in range is not a clean bill of health and a result outside it is not a diagnosis. Most ranges cover about 95% of healthy people, so about 1 in 20 healthy people fall just outside any one range. No test result replaces an examination or your own doctor’s judgement, and none of these panels is a cancer screening programme.

Read the full note

The reference range printed beside each of your results is the laboratory's own, and it is the range that applies to your result. We do not apply a second range of our own, and we do not tell you that a result the laboratory reported as normal is nonetheless too low or too high. If you see a claim elsewhere that your result ought to sit inside a narrower band than the one the laboratory printed, treat it with caution and ask your doctor.

Some assays cannot give an exact figure above or below a certain point, and those results are reported the way the laboratory sends them, for example as a value greater than a stated number. A result in range is not a clean bill of health, and a result outside a range is not a diagnosis: most reference ranges are set to cover about 95% of healthy people, so some healthy people fall just outside them. No blood test replaces an examination, a scan or your own doctor's judgement, and none of these panels is a screening programme for cancer.

If you have a symptom that is new, severe, or getting worse, contact your GP or NHS 111 rather than waiting for a test result. In an emergency call 999.

Frequently asked questions

When in my cycle should I take the sample?

If you are having periods at all, day two to five of a bleed is the standard timing. If you have not had a period for months there is no cycle day to aim for, so any day is fine and the report reads the results on that basis.

Should I stop hormonal contraception first?

No. Do not stop contraception in order to test. The combined pill, patch and ring change these results considerably, the injection and implant can too, and the hormonal coil usually has less effect. Tell us what you use and the reviewing doctor reads the results in that light.

What is the free androgen index?

It is a calculation from your testosterone and SHBG together, which estimates how much testosterone is actually available to the body. It is often more informative than testosterone alone, particularly when irregular periods and acne go together.

Is this a test for polycystic ovary syndrome?

It measures hormones that are part of that assessment, including testosterone and the free androgen index. PCOS is recognised from your periods and symptoms as well as blood tests, sometimes with a scan, and no blood panel settles it on its own. If PCOS is the specific question, the PCOS Check adds blood sugar, cholesterol, insulin and AMH. The PCOS Essentials Check adds blood sugar and cholesterol but does not include testosterone.

I use hormone cream or gel. Does that affect the sample?

It can. Hormone from cream or gel on your skin, such as HRT or testosterone gel, can get into a finger-prick sample and give a falsely high result. Wash your hands first, do not take the sample from a finger or area where cream or gel has been applied, and if you apply gel to your hands, use the other hand.

Does biotin affect the result?

It can. High-dose biotin (vitamin B7), often sold for hair, skin and nails, can make some hormone results read too high or too low. Laboratory advice is usually to leave at least 8 hours after a dose of 5 mg or more, and some advise longer, so the simplest approach is to skip it on the day of your sample. Tell us if you take it, and do not stop a medicine that a doctor has prescribed.

How long do results take?

The laboratory typically takes 1 to 2 working days from receiving your sample. This does not include kit delivery, sample collection or return postage. A doctor reviews your results before they are released.

Can I choose a home kit or a clinic?

Both, it is your choice at checkout. Either collect a finger-prick sample at home with the posted kit and send it back as the instructions explain, or book a clinic appointment and have a trained clinician take the sample for you.

Is a doctor involved?

Yes. Every result is reviewed by a GMC-registered doctor who signs it off and explains what it means and what to do next.

Is it confidential?

Your results are available through your secure patient portal. Our privacy policy explains how your information is handled and when it may be shared to provide your care.

What happens to my sample and results?

Your sample is analysed at a UKAS-accredited laboratory (ISO 15189). A GMC-registered doctor then reads every result and signs the report before it is released, so nothing reaches you unreviewed. There is no option to receive results without a doctor reading them first. The report arrives in your secure portal in plain English: each result with its unit and the laboratory's own reference range, and the doctor's note on what the set means read together. If a result sits outside its range the report says so and explains what usually happens next, which is most often a conversation with your own GP, who can act on it alongside your history and examination. Most reference ranges are set to cover about 95% of healthy people, so about 1 in 20 healthy people fall just outside any one of them. On a report with many results it is common for one to sit just outside its range, and a single number on its own rarely tells the whole story. If a result needs urgent attention, the reviewing doctor is alerted straight away and we contact you by phone the same working day rather than leaving it in the portal for you to find. If a specific result needs rechecking, the reviewing doctor says so in your report.

Doctor-reviewed results
In plain English, signed by a GMC-registered doctor
Laboratory testing
Read each test’s coverage and limitations
No GP referral
Order directly, no waiting list
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Secure results, your own private portal

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