Clinic appointment
HRT Hormone Check
FSH, oestradiol and progesterone together, for people who want a hormone picture around starting or reviewing hormone replacement therapy.
- Doctor-reviewed results
- Laboratory analysis
- 1 to 2 working days from lab receipt
- No fasting required

What’s included
3 markers measured
FSH
Follicle-stimulating hormone. As the ovaries become less active in the years before the menopause, less feedback reaches the pituitary gland and FSH rises. Levels can swing sharply from day to day during this change, then stay high after the menopause.
Oestradiol
An oestrogen hormone, often checked with FSH, LH and prolactin when periods have stopped. A low level can point to early loss of ovarian function (with a high FSH), a raised prolactin, or causes such as weight loss, stress or heavy exercise. Results are not reliable during any hormonal treatment.
Progesterone
A hormone measured midway through the second half of the menstrual cycle to confirm that ovulation has happened. With a regular 28-day cycle it is usually taken on day 21; with longer, irregular cycles it is timed later and may be repeated weekly until the next period.
Overview
FSH, oestradiol and progesterone together describe where the ovaries are in the menopause transition and what the two main cycle hormones are doing. People order it when they are thinking about hormone replacement therapy, or already using it and want a picture before a review appointment.
These three results describe where the ovaries are in the menopause transition and what oestrogen and progesterone are doing. Blood levels are only part of the picture, and UK guidance is clear that over 45 the decision about hormone replacement rests on symptoms rather than on a blood test. If you are already using patches, gel or tablets the numbers reflect the treatment as well as the ovaries, so the timing of the sample relative to your usual dose changes what they mean. Any change to treatment is a conversation with the clinician who looks after it.
Who this is for and who it isn’t
Who it’s for
- Women aged 18 and over
- Women under 45 whose periods have changed and who want the hormone picture
- Anyone preparing for a hormone replacement review appointment
Who it isn’t for
- Over 45, UK guidance is clear that the decision about hormone replacement rests on symptoms rather than on blood levels, so this rarely changes what happens. It also does not include thyroid function, and thyroid problems can cause symptoms that overlap with menopausal ones: the HRT Hormone Check Plus adds it. If you already use patches, gel or tablets, the numbers reflect the treatment as well as your ovaries.
- We do not provide or adjust hormone replacement therapy.
- Anyone with a new, severe or worsening symptom: contact your GP or call NHS 111. A test you buy today is not a substitute for being examined.
Common reasons people choose this test
- Hot flushes, night sweats or disturbed sleep
- Periods becoming irregular or stopping under 45
- Considering hormone replacement therapy and wanting a baseline
- Already using HRT and preparing for a review
- Mood or memory changes you want a hormone picture for
These are reasons people choose to test, not signs that something is wrong. A result is one part of a picture your doctor puts together with your history and an examination.
What your result looks like
Every result is shown with the unit and the reference range exactly as the laboratory reported it, with the doctor’s note underneath.
- FSH▲ High
- Result
- 34 IU/L
- Range
- 3.5–12.5 (day 2–5)
- OestradiolIn range
- Result
- 210 pmol/L
- Range
- 98–571 (day 2–5)
- ProgesteroneIn range
- Result
- 42 nmol/L
- Range
- >30 (7 days before period due)
| Marker | Result | Units | Range | Flag |
|---|---|---|---|---|
| FSH | 34 | IU/L | 3.5–12.5 (day 2–5) | ▲ High |
| Oestradiol | 210 | pmol/L | 98–571 (day 2–5) | In range |
| Progesterone | 42 | nmol/L | >30 (7 days before period due) | In range |
Doctor’s note (example)
FSH above 30 with irregular periods and symptoms points towards the menopause transition. Under 45 it is repeated in six weeks before any conclusion.
Values above are examples. Your report shows your own results with the laboratory’s units and reference range for your age and sex, reviewed, signed and released by a GMC-registered doctor.
How it works
- You book your appointmentA trained clinician takes your sample at one of our London clinics. Nothing to do at home.
- The clinician takes your sampleA single clinic blood draw by a trained clinician
- The laboratory analyses itYour sample is processed for the measurements included in this test. Lab processing typically takes 1 to 2 working days from receipt of your sample.
- A doctor reviews and releases itA GMC-registered doctor reads every result and signs the report before it reaches you.
- Sample
- Clinic blood draw
- Preparation
- No fasting required
- Who it's for
- Women · ages 18+
How to prepare
What we can and can’t tell you
The reference range beside each result is the laboratory’s own. A result in range is not a clean bill of health and a result outside it is not a diagnosis. Most ranges cover about 95% of healthy people, so about 1 in 20 healthy people fall just outside any one range. No test result replaces an examination or your own doctor’s judgement, and none of these panels is a cancer screening programme.
Read the full note
The reference range printed beside each of your results is the laboratory's own, and it is the range that applies to your result. We do not apply a second range of our own, and we do not tell you that a result the laboratory reported as normal is nonetheless too low or too high. If you see a claim elsewhere that your result ought to sit inside a narrower band than the one the laboratory printed, treat it with caution and ask your doctor.
Some assays cannot give an exact figure above or below a certain point, and those results are reported the way the laboratory sends them, for example as a value greater than a stated number. A result in range is not a clean bill of health, and a result outside a range is not a diagnosis: most reference ranges are set to cover about 95% of healthy people, so some healthy people fall just outside them. No blood test replaces an examination, a scan or your own doctor's judgement, and none of these panels is a screening programme for cancer.
If you have a symptom that is new, severe, or getting worse, contact your GP or NHS 111 rather than waiting for a test result. In an emergency call 999.
Frequently asked questions
Do I need this before starting HRT?
Usually not, if you are over 45 and have typical symptoms; UK guidance does not require blood tests to start. Under 45 blood tests do have a place, and some people simply want the numbers before a conversation.
When should I take the sample if I already use HRT?
Follow whatever your prescriber has advised, and use the same timing relative to your dose each time so results are comparable. Levels vary enormously between patches, gel and tablets.
Which day of my cycle?
If you are still having periods, day two to five of a bleed. If your periods have stopped, any day is fine.
Can I use the result to change my dose?
No. Dose decisions belong with the clinician who looks after your treatment, who reads levels alongside your symptoms. The report explains what the numbers mean so that conversation starts from a better place.
I use oestrogen gel or spray. Does that affect the blood test?
It can. Gel on the skin near where the needle goes in can make oestradiol read falsely high. Tell the nurse where you applied it, so the sample is taken from an arm you have not used it on that day.
Does biotin affect the result?
It can. High-dose biotin (vitamin B7), often sold for hair, skin and nails, can make some hormone results read too high or too low. Laboratory advice is usually to leave at least 8 hours after a dose of 5 mg or more, and some advise longer, so the simplest approach is to skip it on the day of your sample. Tell us if you take it, and do not stop a medicine that a doctor has prescribed.
How long do results take?
The laboratory typically takes 1 to 2 working days from receiving your sample. This does not include kit delivery, sample collection or return postage. A doctor reviews your results before they are released.
Can I choose a home kit or a clinic?
This test is a clinic blood draw, as it needs a venous sample for accuracy. We arrange a convenient appointment for you.
Is a doctor involved?
Yes. Every result is reviewed by a GMC-registered doctor who signs it off and explains what it means and what to do next.
Is it confidential?
Your results are available through your secure patient portal. Our privacy policy explains how your information is handled and when it may be shared to provide your care.
What happens to my sample and results?
Your sample is analysed at a UKAS-accredited laboratory (ISO 15189). A GMC-registered doctor then reads every result and signs the report before it is released, so nothing reaches you unreviewed. There is no option to receive results without a doctor reading them first. The report arrives in your secure portal in plain English: each result with its unit and the laboratory's own reference range, and the doctor's note on what the set means read together. If a result sits outside its range the report says so and explains what usually happens next, which is most often a conversation with your own GP, who can act on it alongside your history and examination. Most reference ranges are set to cover about 95% of healthy people, so about 1 in 20 healthy people fall just outside any one of them. On a report with many results it is common for one to sit just outside its range, and a single number on its own rarely tells the whole story. If a result needs urgent attention, the reviewing doctor is alerted straight away and we contact you by phone the same working day rather than leaving it in the portal for you to find. If a specific result needs rechecking, the reviewing doctor says so in your report.
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